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  • Title: [Testicular tumors in male pseudohermaphroditism].
    Author: Bobokhidze NV, Bronshteĭn ME, Golubeva IV, Iur'eva NP.
    Journal: Probl Endokrinol (Mosk); 1984; 30(6):28-34. PubMed ID: 6514682.
    Abstract:
    The data are summarized on the incidence and morphofunctional characteristics of gonadal tumors in different varieties of false male hermaphroditism, namely the testicular feminization syndrome (marked and unmarked forms), demonstrable masculinization and dysgenesis and compared with the disease clinical manifestations. The two syndromes--testicular feminization (marked form) and dysgenesis were found to be associated with a high risk of cancer development. In the first case there develop sertolioma-like tumors and in the second one, tumors similar to gonocytoma and dysgerminoma. These tumors became malignant in rare cases, they did not recur or metastasize. The treatment schedule for such patients has been developed. It includes the removal of the tumor-affected gonads and transfer of the tumor-free gonads into subcutaneous abdominal or scrotal areas and administration (during castration) of continuous substitution hormonotherapy according to the sex chosen.
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