These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Mechanism of action of dialkylaminoethylthiol derivatives of pyrimidine and quinazoline].
    Author: Tregubenko IP, Tarakhtiĭ EA, Chibiriak MV, Golomolzin BV, Egorova LG.
    Journal: Radiobiologiia; 1984; 24(6):838-42. PubMed ID: 6515015.
    Abstract:
    A study was made of acute toxicity and radioprotective efficiency of some heterocyclic isothiuronium analogues and their ability to change the oxygen uptake by the organism. The rate of hydrolysis of the preparations in vitro was determined. A correlation was found between the above-mentioned indices. On the basis of the data obtained it was concluded that aminothiol, formed as the result of enzymic digestion in the organism, was responsible for the radioprotective effect of the compounds under study since it reduced the oxygen uptake by the organism.
    [Abstract] [Full Text] [Related] [New Search]