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Title: Inhibition of acetate incorporation into lipids by adriamycin. Author: Okano C, Hokama Y, Chou SC. Journal: Res Commun Chem Pathol Pharmacol; 1984 Nov; 46(2):293-6. PubMed ID: 6515121. Abstract: Adriamycin (ADM) inhibits 14C-acetate incorporation into cardiomyocytes, with the ID50 being 0.9 microM. Incorporation into neutral lipids were inhibited except for cholesterol ester. Cholesterol and phospholipids demonstrated the strongest inhibition at 5 microM ADM.[Abstract] [Full Text] [Related] [New Search]