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  • Title: Dysfibrinogenaemia associated with a defect in the aggregation of the fibrin monomers (Almeria I fibrinogen). A preliminary study.
    Author: Vila V, Regañon E, Fernandez-Pavon A, Aznar J.
    Journal: Scand J Haematol; 1984 Nov; 33(5):460-5. PubMed ID: 6515329.
    Abstract:
    A patient with functionally defective fibrinogen has been studied. Fibrinogen Almeria I was found to have a prolonged of latency time (LT) and a decrease in rate of gelation (RG) when plasma or isolated fibrinogen were activated by thrombin or reptilase. This fibrinogen also has the unusual formation of cross-linked fibrin; the existence of unpolymerized alpha chains was confirmed.
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