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  • Title: Faecal chymotrypsin for investigation of exocrine pancreatic function: a comparison of two newly developed tests with the titrimetric method.
    Author: Ehrhardt-Schmelzer S, Otto J, Schlaeger R, Lankisch PG.
    Journal: Z Gastroenterol; 1984 Nov; 22(11):647-51. PubMed ID: 6516499.
    Abstract:
    Two newly developed photometric assays for the estimation of faecal chymotrypsin were studied in comparison with the established titrimetric method in 46 patients and 8 healthy volunteers, who had undergone a secretin-pancreozymin test for diagnostic purposes. The correlation between the two photometric methods and the titrimetric method was good (r = 0.90 and r = 0.91), revealing similar diagnostic sensitivity and specificity. As both photometric methods are less time-consuming and may be performed using a standard laboratory equipment, they offer a good alternative to the established titrimetric method for faecal chymotrypsin estimation.
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