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  • Title: Progesterone enhances reactive oxygen intermediates production by cultured human monocytes.
    Author: Martinoli C, Zocchi E, Querzola F, Damiani G, Zaccheo D.
    Journal: Boll Soc Ital Biol Sper; 1984 Oct 30; 60(10):1871-7. PubMed ID: 6518099.
    Abstract:
    Progesterone at placental tissue concentrations (5-20 micrograms/ml) markedly increases in vitro PMA-stimulated O-2 and H2O2 production by human cultured monocytes. This appears to contrast the well-known suppressive action of the hormone on the other cell mediated defence mechanisms. We suggest that these findings could cast a new light on progesterone's multiple and differentiated functions in the placental environment.
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