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Title: Investigation on the carcinogenicity of emission condensate from brown coal-fired residential furnaces applied to mouse skin. Author: Deutsch-Wenzel RP, Brune H, Grimmer G, Dettbarn G, Misfeld J, Timm J. Journal: Cancer Lett; 1984 Nov; 25(1):103-11. PubMed ID: 6518447. Abstract: Flue gas condensate emitted from brown coal-fired stoves was tested in 3 dosages applied chronically to the skin of female CFLP mice twice a week over a period of 104 weeks. To answer the question which portion of the total carcinogenicity results from benzo[a]pyrene (BaP), this compound was taken as reference substance. The probit and Weibull analysis of the results showed a linear dose-response relationship for both tumor incidences and tumor induction times. The amount of BaP in the emission condensate (0.593 mg/g condensate) contributes about 15% to the total carcinogenic effect of the brown coal flue gas condensate.[Abstract] [Full Text] [Related] [New Search]