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  • Title: [Effect of GABA and piracetam on cerebral circulation and the neurogenic mechanisms of its regulation].
    Author: Ivashev MN, Petrov VI, Shcherbakova TN.
    Journal: Farmakol Toksikol; 1984; 47(6):40-3. PubMed ID: 6519254.
    Abstract:
    Resistography was applied in acute cat experiments to study the effects of GABA and piracetam on the neurogenic pressor vascular reactions of cerebral and hind limb vessels, induced by stimulation of bulbar structures (locus coeruleus field), of the cervical sympathetic and tibial nerves. GABA (50 mg/kg) and piracetam (100 mg/kg) reduced the central and reflex evoked contractions of the cerebral vessels but enhanced their reflex evoked reactions. A possible mechanism of such drug actions is discussed.
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