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  • Title: Clinical pharmacology of hypertension: amelioration of left ventricular performance by treatment with labetalol.
    Author: Belogi M, Ansuini R, Pupita G, Campolucci G, Pupita F.
    Journal: Int J Clin Pharmacol Res; 1984; 4(5):385-7. PubMed ID: 6519853.
    Abstract:
    Treatment of 23 hypertensive patients with labetalol at 200 mg twice daily for 3 months resulted in a 15-17% reduction in diastolic and systolic blood pressure, a significant amelioration in the PEP/LVET ratio expressing the haemodynamic performance of the left ventricle, and a significant reduction in its hypertrophy as expressed by the Romhilt-Estes index.
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