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  • Title: A multivariate analysis of the risk indicators of reduction limb defects.
    Author: Aro T, Haapakoski J, Heinonen OP.
    Journal: Int J Epidemiol; 1984 Dec; 13(4):459-64. PubMed ID: 6519885.
    Abstract:
    In order to evaluate associations of various selected risk indicators with reduction limb defects, data on 453 cases of reduction limb defects and their time-area matched pair controls from the Finnish Registry of Congenital Malformations was studied. A multivariate analysis of the earlier reported associations was performed. This analysis showed that the following risk indicators were associated with the defects: high birth order, threatened abortion, low placental weight, low birth weight, previous malformations in the family, influenza during early pregnancy, other infectious diseases, and mother's alcohol consumption during pregnancy.
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