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  • Title: [Clinical and cisternographic differential diagnosis between presenile dementia and Hakim syndrome].
    Author: Kulczycki J, Jedrzejczak T.
    Journal: Psychiatr Neurol Med Psychol (Leipz); 1984 Nov; 36(11):674-7. PubMed ID: 6522522.
    Abstract:
    The authors compared with regard clinical and the radionuclide cisternography examination 27 patients with Hakim-Syndrome and 11 with Alzheimer-Disease. In all cases, dementia was a stable symptom. Patients with Hakim-Syndrome have an early gait disturbance, ataxia and epileptic seizures. Only in case of patients with Alzheimer-Disease we found aphasia, apraxia and psychotic disorders. 24 hours after the injection radionuclide cisternography showed ventricular retention and absence of parasagital accumulation only in patients with Hakim-Syndrome. Lighter changes (mixed cisternographic pattern) were found in patients with Alzheimer-Disease as well.
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