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  • Title: Influence of blood-taking procedure on the heart function of blood donors.
    Author: Ibler M, Lage S.
    Journal: Acta Anaesthesiol Scand; 1984 Dec; 28(6):587-90. PubMed ID: 6524273.
    Abstract:
    The systolic time intervals and heart rate were studied in 11 blood-donors aged between 20 and 48 years by a non-invasive technique before and after the usual blood-taking procedure. No statistically significant difference was found between values determined before and after the procedure. A significant correlation (r = 0.76) was demonstrated between percent changes of pre-ejection period/left ventricular ejection time (PEP/LVET)-ratio and withdrawn volume of blood (450 ml) X time (min)-1 X bodyweight (kg)-1. No correlation was found between percent changes of PEP/LVET-ratio and withdrawn volume of blood X time-1, nor between percent changes of PEP/LVET-ratio and withdrawn volume of blood X percentage of circulatory volume removed-1. It is suggested that the blood-taking time (in minutes) should not be shorter than the quotient: donated volume of blood (ml) X bodyweight (kg)-1 if a negative influence of withdrawal procedure on left ventricular function is to be avoided. Mechanisms contributing to circulatory stability during reduction of blood volume are briefly discussed.
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