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  • Title: [Symptomatic urinary infection in infants less than 4 months old: outcome in 129 cases].
    Author: Navarro M, Espinosa L, de las Heras JA, García Meseguer MC, Peña MA, Larrauri M.
    Journal: An Esp Pediatr; 1984 Oct 31; 21(6):564-72. PubMed ID: 6524767.
    Abstract:
    A series of 129 children with urinary infection during the first 120 days of life, were followed-up for periods ranging from to 1 to 16 years (means = 4 1/12 year). They have been separated in two groups, depending on urocystographic findings: (I) with mild lesions and/or reflux (99 cases) and (II) with obstructive uropathy (30 cases). All the patients in group II and those with reflux of grade IV received surgical treatment. The remaining ones received chemoprophylaxis. During the follow-up, all grade I refluxes disappeared, and so did 86% of grade II and 58% of grade III. Pyelonephritic scars are present in 34% of those kidneys with grade III reflux, 56% of grade IV and 88% of those of the group II. Permanent alteration of renal function was found almost exclusively in patients with grade IV reflux or obstructive anomalies bearing no relation with the number of recurrences of infection during the follow-up.
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