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  • Title: The mesencephalic locomotor region (MLR) in the rat.
    Author: Skinner RD, Garcia-Rill E.
    Journal: Brain Res; 1984 Dec 10; 323(2):385-9. PubMed ID: 6525525.
    Abstract:
    These studies demonstrate the presence of the MLR in the rat brain. Controlled locomotion on a treadmill could be induced by low level stimulation (less than 50 microA) of an area in the posterior midbrain following a precollicular-prenigral brainstem transection. This area included the lateral part of the cuneiform nucleus and anterior as well as posterior portions of the pedunculopontine nucleus. In addition, the presence of a subthalamic locomotor region in the fields of Forel was determined in rats after prethalamic transections.
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