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  • Title: Hyperprolactinemia fails to increase striatal dopamine receptors in male and female C57BL/6J mice.
    Author: Morgan DG, Mobbs CV, Anderson CP, Sinha YN, Finch CE.
    Journal: Eur J Pharmacol; 1984 Dec 15; 107(1):101-4. PubMed ID: 6526068.
    Abstract:
    Mice were administered prolactin by either homotypic anterior pituitary grafts (4 weeks) or subcutaneous osmotic pumps containing ovine prolactin (1 week). The pituitary grafts produced considerably greater elevations of circulating prolactin than the osmotic pumps. In neither case was any change detected in striatal [3H]spiperone binding to dopamine receptors. These results are discussed in the context of contradictory evidence obtained with rats.
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