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Title: Crystalline monoclonal antibody Fabs complexed to hen egg white lysozyme. Author: Silverton EW, Padlan EA, Davies DR, Smith-Gill S, Potter M. Journal: J Mol Biol; 1984 Dec 15; 180(3):761-5. PubMed ID: 6527381. Abstract: The Fab of a monoclonal anti-lysozyme antibody (HyHEL-10) has been crystallized as the free Fab and as the Fab-antigen complex. Crystals have also been grown of the antigen complex of the Fab of another monoclonal anti-lysozyme antibody (HyHEL-9), which recognizes a different binding surface of lysozyme. All three crystals diffract to at least 3 A resolution and are suitable for X-ray diffraction studies.[Abstract] [Full Text] [Related] [New Search]