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  • Title: Single case experiments in psychopharmacological trials.
    Author: Wolfrum C, Klieser E, Lehmann E.
    Journal: Neuropsychobiology; 1984; 12(2-3):152-7. PubMed ID: 6527757.
    Abstract:
    Single case experiments have been used to make pharmacotherapeutic decision making more objective. 4 single case experiments are presented. In the case of 3 patients the question was whether flunitrazepam (Rohypnol) should be administered. In the 4th patient the issue was whether self-administration of Limbitrol (amitriptyline + chlordiazepoxide) should be terminated. Planning and analysis of these experiments was carried out by the randomization test.
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