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  • Title: [Long-term development of eosinophilic fasciitis. Study of 11 cases].
    Author: Herson S, Piette JC, Frances C, Etienne SD, Le Thi Huong Du, Mouthon JM, Blétry O, Wechsler B, Godeau P.
    Journal: Ann Med Interne (Paris); 1984; 135(8):611-4. PubMed ID: 6529057.
    Abstract:
    The long-term outcome of eosinophilic fasciitis (EF) described for the first time by Shulman in 1974 remains unclear. Its exact pathological classification is still contested. We reviewed 11 cases selected exclusively on their initial symptoms being compatible with EF. The outcome of the cutaneous lesions, the investigations of possible visceral involvement were analysed with a follow-up of 1 to 9.5 years (average 4.8 years). Regression of the cutaneous infiltration was complete in 5 cases and partial in 3 cases. No regression was observed in 3 cases. Steroid therapy was given in 10 patients: objective improvement was observed in 5 patients. There was no improvement in the other 5 cases. Ungual capillaroscopy was performed in 9 patients and showed none of the characteristic capillary changes of scleroderma. These results suggest that the prognosis and outcome of EF justify its distinction from systemic scleroderma. The effects of steroid therapy on the cutaneous lesions are very variable.
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