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  • Title: The plasma and erythrocyte fatty acid composition of poorly controlled, insulin-dependent (type I) diabetic patients and the effect of improved metabolic control.
    Author: van Doormaal JJ, Muskiet FA, van Ballegooie E, Sluiter WJ, Doorenbos H.
    Journal: Clin Chim Acta; 1984 Dec 29; 144(2-3):203-12. PubMed ID: 6529855.
    Abstract:
    Analysis of the plasma and erythrocyte fatty acid composition of poorly controlled, insulin-dependent (type I) diabetic patients revealed a low level of 18:3c, omega 6, 20:3c, omega 6, 22:6c, omega 3 and total polyunsaturated fatty acids, and a high level of 18:0 and total saturated fatty acids. Improvement of diabetic control, achieved by treatment with continuous subcutaneous insulin infusion coincided with an increase of arachidonic acid and a normalization of total polyunsaturated fatty acids, with a concomitant decrease of total saturated fatty acids and total monounsaturated fatty acids, especially 18:1c, omega 9. The results of this study can be important for the dietary advice to poorly controlled, diabetic patients.
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