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  • Title: [Urinary tract infections: new approaches].
    Author: Varese LA, Grazioli F, Antoniola P, Viretto A, Vighetti A.
    Journal: Pediatr Med Chir; 1984; 6(1):57-64. PubMed ID: 6531241.
    Abstract:
    Evidence that cure in acute, uncomplicated UTI will be achieved with a single-dose treatment is reported. In according with experimental works on pyelonephritis and pharmacological and pharmacocynetic data on new aminoglycoside antibiotics, authors proposed a new approach in the management of UTI, acute bacterial pyelonephritis and asymptomatic bacteriuria in children. Association of bolus dose therapy, non chemoantibiotical control of periurethral and intestinal ecosystem, with frequent and systematic monitoring of bacteriuria, seems to be effective to control infection and to prevent the development of renal scarring. Management of UTI in childhood could be easier and not require intensive and prolonged courses of antimicrobial therapy.
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