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Title: Effects of vitamin E in kid erythrocytes on Tween 20-induced hemolysis in vitro. Author: Hodate K, Hamada T. Journal: J Nutr Sci Vitaminol (Tokyo); 1984 Dec; 30(6):509-14. PubMed ID: 6533271. Abstract: Red blood cells (RBC) of alpha-tocopherol sufficiency and deficiency were produced in kids fed on purified diets to investigate the relationship between RBC alpha-tocopherol levels and hemolysis induced by Tween 20. RBC alpha-tocopherol contents of vitamin E-deficient kids were non-detectable from 4 weeks, and percentages of hemolysis increased to over 70%. A highly significant decrease in hemolysis was noted when vitamin E was added to the diet. Tween 20 hemolysis values were negatively correlated with RBC tocopherol levels in kids. The concentration of RBC alpha-tocopherol required to prevent the hemolysis was found to be 0.6 microgram/ml packed cells.[Abstract] [Full Text] [Related] [New Search]