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  • Title: Sensitization of combined cis-platinum and cyclophosphamide by local hyperthermia in mice bearing the Lewis lung carcinoma.
    Author: Hazan G, Lurie H, Yerushalmi A.
    Journal: Oncology; 1984; 41(1):68-9. PubMed ID: 6538329.
    Abstract:
    The combined effect of cis-platinum cyclophosphamide, and local hyperthermia was investigated in mice bearing the metastatic Lewis lung carcinoma. The combined action of cyclophosphamide and cis-platinum resulted in an additive effect. The triple combination of cis-platinum, cyclophosphamide and local hyperthermia revealed thermal potentiation of the combined drug-induced growth delay.
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