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  • Title: A comparison between the efficacy of thiabendazole and febantel on experimental trichinellosis in rats.
    Author: Alcaíno HA, Gorman TR, Elorrieta MB.
    Journal: Vet Parasitol; 1984 Mar; 14(2):153-7. PubMed ID: 6538721.
    Abstract:
    Febantel at a dose level of 5 mg kg-1 had a lethal efficacy of 54.1% against the adult worm and 69.5% against the migrating larvae of Trichinella spiralis in rats. When administered at 15 mg kg-1, it demonstrated lethal effects of 94.4, 92.5 and 74.7% against adult, young and encysted larvae, respectively. Infected rats treated with 300 mg kg-1 died. Thiabendazole had efficiencies of 96.4 and 83.3% against intestinal and migrating early muscle phases, respectively, and was 42% effective against the encysting phase.
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