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  • Title: [Potential for dependence of analgesics and psychopharmaceuticals].
    Author: Hoffmeister F.
    Journal: Arzneimittelforschung; 1984; 34(9A):1096-107. PubMed ID: 6541933.
    Abstract:
    The dependence liability of analgesic and psychotropic drugs as assessed in animal experiments is described. It is demonstrated that the abuse liability of a given drug does not only depend on its pharmacological or psychopharmacological profile of actions. The abuse liability of a drug is, however, greatly influenced by environmental variables, motivation to self-administration of a drug as well as previous drug exposure. Correlations between dependent behavior of animals and dependent behavior of men are discussed.
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