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  • Title: Clinical evaluation of amitraz as a treatment for canine demodicosis.
    Author: Folz SD, Kakuk TJ, Henke CL, Rector DL, Tesar FB.
    Journal: Vet Parasitol; 1984 Nov; 16(3-4):335-41. PubMed ID: 6542729.
    Abstract:
    A liquid concentrate formulation of amitraz was clinically evaluated in 1721 canines showing demodicosis, by 25 veterinary investigators. The therapy was applied topically at 14-day intervals, and at a concentration of 250 ppm active drug in water. The miticide was efficacious and safe; approximately 99% of the canines showing localized or generalized demodicosis became clinically normal, and the side-effects recorded were minimal and transient. Approximately 3/4 of the patients were pure-bred animals and the majority were less than 1 year old. The clinical data support the conclusion that amitraz (liquid concentrate) is efficacious and safe for treating canine demodicosis.
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