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  • Title: [Effect of spirobramin and prospidin on immunogenesis].
    Author: Gol'dberg ED, Mikhaĭlova TN, Zinger GV, Potapova GV, Chernov VA.
    Journal: Farmakol Toksikol; 1984; 47(6):56-9. PubMed ID: 6542876.
    Abstract:
    The immunosuppressant effects of the antineoplastic piperazine drugs spirobramine and prospidin in respective doses of 500 and 600 mg/kg (1/2 of the LD50) were studied in experiments on cats. Spirobramine was shown to exert a more pronounced immunoinhibitory action on the primary and secondary immune response induced by sheep red blood cells.
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