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  • Title: [Features of the structure of the mesenteric and tracheobronchial lymph nodes in rat offspring after exposure to tetracycline].
    Author: Savitskaia TN.
    Journal: Arkh Anat Gistol Embriol; 1984 Nov; 87(11):66-72. PubMed ID: 6543113.
    Abstract:
    Ante- and postnatal development of anatomical structures and cells of lymphatic nodes has been studied in rat offspring subjected to tetracycline effect during placentation and organogenesis (the 8th-14th days) and during fetogenesis (the 15th-20th days). Tetracycline injection during the 8th-14th days of embryogenesis results in certain disturbances of the nodular structure formations, inhibition of lympho- and plasmo-cytopoesis against the background of a sharp increase in number of basophilic granulocytes and tissue basophils. The antibiotic effect on the 15th-20th days of embryogenesis does not disturb the lymph node formation, but produces an increasing number of lymphocytes, plasmocytes, macrophages, eosinophilic granulocytes and tissue basophils in them.
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