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  • Title: Comparison of the Lumadex-foam stability index test, lecithin: sphingomyelin ratio, and simple shake test for fetal lung maturity.
    Author: Lipshitz J, Whybrew WD, Anderson GD.
    Journal: Obstet Gynecol; 1984 Mar; 63(3):349-54. PubMed ID: 6546612.
    Abstract:
    Amniotic fluid was obtained from 269 patients within 72 hours of delivery. The sensitivity, specificity, and predictive value of the Lumadex-foam stability index test, lecithin: sphingomyelin (L:S) ratio, and simple shake test were assessed in the diagnosis of respiratory distress syndrome (RDS), as well as the accuracy in identification of functional lung maturity in the growth-retarded fetus. The Lumadex-foam stability index test was found to be an accurate, quantitative, simple, and rapid measure of fetal lung maturity in the normal as well as abnormal pregnancy. The L:S ratio was accurate in the normal pregnancy, but became inaccurate in the small growth-retarded fetus. The nonquantitative simple shake test was accurate when it indicated fetal lung maturity, but an immature result was meaningless because of the large false-negative rate.
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