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  • Title: [Use of adriamycin in the treatment of metastatic breast cancer].
    Author: Dymarskiĭ LIu, Sanchakova AV, Aleksandrova GI, Trishkina EA.
    Journal: Vopr Onkol; 1984; 30(6):67-73. PubMed ID: 6547554.
    Abstract:
    Adriamycin (alone and as a component of FAC scheme) should be administered to patients with disseminated breast cancer resistant to cytostatic drugs. This treatment is followed by remission and arrests the process for an average of 9 months (in some cases up to 30 months). Mean doses of 30-40 mg should be given to outpatients on days 1 and 8 of each course, with intervals between courses being 21-28 days. No apparent side-effects are observed. The total dose should be as high as 450-550 mg. Adjuvant antiestrogen treatment (tamoxifen) should be given to pre- and menopausal patients.
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