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  • Title: [Thyroid pathology of newborn infants of mothers with Basedow's disease].
    Author: Landier F, Chaussain JL, Job JC.
    Journal: Arch Fr Pediatr; 1984 Mar; 41(3):163-6. PubMed ID: 6547586.
    Abstract:
    Of 15 neonates born to mothers presenting with Graves' disease, who were admitted for presumptive thyroid disorder, 6 presented with neonatal thyrotoxicosis, 4 with goiter and/or hypothyroidism, and 5 presented with euthyroidism. In cases with thyrotoxicosis, the mothers were not or insufficiently treated. Evolution was regressive in 5 instances, there was a craniostenosis and persisting hyperthyroidism in one case. In cases with goiter and/or hypothyroidism, on the other hand, the mothers were correctly treated, and neonatal manifestations were benign and transient. This emphasizes both the importance of supervising gravidic hyperthyroidism and the complexity of materno-foetal relationship in thyroid diseases.
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