These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Giant lamellar bodies in alveolar type II cells of rats exposed to a low concentration of ozone.
    Author: Shimura S, Maeda S, Takismima T.
    Journal: Respiration; 1984; 46(3):303-9. PubMed ID: 6548572.
    Abstract:
    The effect of a low concentration of ozone on pulmonary surfactant release was examined by the ultrastructural morphometry of lamellar bodies in alveolar type II cells. Rats were exposed to approximately 0.3 ppm of ozone for 3 h daily for 16 consecutive days. The volume density of lamellar bodies, relative to the cell, increased significantly following ozone exposure. After 11 days giant lamellar bodies were found in ozone-exposed rats. These findings suggest that ozone exposure causes the impairment of pulmonary surfactant release.
    [Abstract] [Full Text] [Related] [New Search]