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  • Title: Fc-receptor function in Henoch-Schönlein disease of childhood.
    Author: Davin JC, Foidart JB, Mahieu PR.
    Journal: Proc Eur Dial Transplant Assoc; 1983; 19():590-6. PubMed ID: 6553913.
    Abstract:
    The Fc-receptor function of circulating monocytes (CM) and/or of splenic macrophages (SM) was followed in eight children presenting with rheumatoid purpura. The Fc-receptor of CM and/or of SM was decreased in all cases during the acute phase of the disease without any correlation with the plasma values of C3, C4, C3PA or immune complexes. When a clinical improvement occurred, a reversal of the Fc-receptor blockade was noted. In contrast, the Fc-receptor function remained abnormal in three children with persistent nephritis. The sequential measurement of Fc-receptor function may be of predictive value in rheumatoid purpura of childhood.
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