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  • Title: Bromocriptine for induction of ovulation in normoprolactinaemic post-pill anovulation.
    Author: van der Steeg HJ, Bennink HJ.
    Journal: Lancet; 1977 Mar 05; 1(8010):502-4. PubMed ID: 65607.
    Abstract:
    19 women with anovulation after discontinuing oral contraceptive agents and with normal plasma-prolactin concentrations were treated with bromocriptine. Ovulation and menstruation were restored in 9 of the 13 amenorrhoeic and 5 of the 6 oligomenorrhoeic patients. The success-rate (74%) indicates that bromocriptine is an effective treatment for post-pill anovulation in normoprolactinaemic women. The therapeutic efficacy of bromocriptine in the treatment of anovulation was assessed in 19 women who failed to return to fertility following discontinuation of oral contraceptive (OC) use. Plasma concentrations of prolactin were normal. Treatment with bromocriptine restored ovulation and menstruation in 9 of the 13 amenorrheic patients and in 5 of 6 oligomenorrheic women. Given the high success rate (74%), it is concluded that bromocriptine is an effective treatment for postpill anovulation in women with normal prolactin levels.
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