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  • Title: GTP interacts with the gamma-subunit of eukaryotic initiation factor eIF-2.
    Author: Kurzchalia TV, Bommer UA, Babkina GT, Karpova GG.
    Journal: FEBS Lett; 1984 Oct 01; 175(2):313-6. PubMed ID: 6566615.
    Abstract:
    Eukaryotic initiation factor eIF-2 is an oligomeric protein consisting of three different subunits. During initiation of protein synthesis eIF-2 interacts with GTP, Met-tRNAf and 40 S ribosomal subunit. By affinity labeling with a photo-reactive GTP analogue it was shown that in the binary complex [eIF-2 X GTP] GTP is in contact with the gamma-subunit of eIF-2.
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