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  • Title: [Agar cultures of blood forming cells from patients with various forms of hemopoietic dysplasia].
    Author: Afanasjew B, Kulibaba T, Lukaschewa T, Smirnowa G, Sabelnia T, Podolzewa E.
    Journal: Z Gesamte Inn Med; 1983 Feb 01; 38(3):67-71. PubMed ID: 6573822.
    Abstract:
    By means of a two-layer agar system the growth-types of blood-forming cells of altogether 47 patients with various forms of the haematopoietic dysplasia were investigated. It could be shown that a hypoplastic and a leukemic growth type as a rule represent a prognostically unfavourable criterion. The probability of a transformation to an acute leukosis is greater in such patients whose blood-forming cells show a leukemic growth in the agar culture. The results of clonization may be used for the differential diagnosis between haematopoietic dysplasia and a number of other diseases. The leukemic growth type was proved in 59% of the patients with haematopoietic dysplasia.
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