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  • Title: Hypoxanthine and Mcardle disease: a clue to metabolic stress in the working forearm.
    Author: Brooke MH, Patterson VH, Kaiser KK.
    Journal: Muscle Nerve; 1983; 6(3):204-6. PubMed ID: 6574314.
    Abstract:
    Forearm exercise in a patient with myophosphorylase deficiency resulted in abnormally high levels of hypoxanthine in the venous blood. The post-exercise hypoxanthine response may reflect ATP depletion in the muscle and provides a useful screening test in muscle diseases with abnormal energy metabolism.
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