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  • Title: Nasal mucociliary transport, number of ciliated cells, and beating pattern in naturally acquired common colds.
    Author: Pedersen M, Sakakura Y, Winther B, Brofeldt S, Mygind N.
    Journal: Eur J Respir Dis Suppl; 1983; 128 (Pt 1)():355-65. PubMed ID: 6578083.
    Abstract:
    Repeated samples of nasal epithelium were taken for in vitro study of the number and motility of ciliated cells (microphoto-oscillographic technique), and nasal mucociliary clearance transport rate was measured (saccharin test) in 26 subjects with naturally acquired common colds. The transport rate was markedly reduced during the disease, and a slight impairment remained even after 32 days. There was a considerable fall in the number of ciliated cells, and regeneration was slow. A moderate and shortlasting change in beating frequency and intracellular synchrony was also observed. It is concluded, that a common cold, as a rule, results in marked and long-lasting impairment of nasal mucociliary clearance function, and this may be the cause of some otherwise unexplainable symptoms from the nose and throat.
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