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  • Title: [Thermochemotherapy for malignant melanoma--combination therapy of ACNU and hyperthermia in mice].
    Author: Yamada K, Someya T, Shimada S, Ohara K, Kukita A.
    Journal: Gan To Kagaku Ryoho; 1983 Oct; 10(10):2179-87. PubMed ID: 6578704.
    Abstract:
    The effect of a combination therapy of hyperthermia (43 degrees C, 30 min) and ACNU (10 mg/kg) on B 16 melanoma and C 24 melanoma in vivo was studied. This combination therapy was effective in both melanoma. In C 24 melanoma, remarkably the tumor regression and the partial destruction of the histological structure, were observed.
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