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  • Title: Prostaglandin D2 stimulates secretion of luteinizing hormone from pituitary gland in vitro.
    Author: Miyake A, Tasaka K, Mori S, Saito Y, Aono T.
    Journal: Acta Endocrinol (Copenh); 1983 Oct; 104(2):164-6. PubMed ID: 6579807.
    Abstract:
    The effect of prostaglandin D2 on the release of luteinizing hormone was studied in a superfusion system by superfusing human pituitary gland. Perfusion with 30 micrograms of prostaglandin D2 induced a significant increase of luteinizing hormone secretion. This is the first evidence of a direct effect of prostaglandin D2 on the secretion of luteinizing hormone from the human pituitary gland. This finding suggests the possible role of prostaglandin D2 in human reproductive function.
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