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  • Title: Collagen and prostaglandin synthesis in force-stressed periodontal ligament in vitro.
    Author: Duncan GW, Yen EH, Pritchard ET, Suga DM.
    Journal: J Dent Res; 1984 May; 63(5):665-9. PubMed ID: 6584472.
    Abstract:
    A periodontal organ culture system capable of receiving orthodontic type forces was developed. Histological, radioautographical, collagen, and prostaglandin synthetic data demonstrated the vitality of the organ over a 24-hour period of culture. Significant increases in the proportion of type III collagen synthesized during periods of active stress were found, but no alterations in relative levels of prostaglandins synthesized during periods of force application were discernible.
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