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  • Title: The role of dental restorative metals in the pathogenesis of oral lichen planus.
    Author: Eversole LR, Ringer M.
    Journal: Oral Surg Oral Med Oral Pathol; 1984 Apr; 57(4):383-7. PubMed ID: 6584832.
    Abstract:
    Twenty-four subjects with oral lichen planus and twelve control subjects without oral mucosal disease were patch tested with dental restorative metals and selected metallic salts. Twenty-one percent of the lichen planus population exhibited a positive skin response to one or more challenge materials, as compared to 8% of the control population. It is concluded that oral lichen planus subjects show a higher correlation with delayed hypersensitivity to dental metals than a control population; however, a cause-and-effect relationship cannot be substantiated.
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