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  • Title: [Neuro-hormonal mechanisms of hypothalamic influences on the tonus of cerebral vessels].
    Author: Teplov SI, Borisova EA, Mikhaĭlova GP.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1978 Apr; 64(4):467-74. PubMed ID: 658515.
    Abstract:
    In anesthetized cats, stimulation of supraoptic nuclei (SON) and dorso-lateral hypothalamus (DLH) led to cerebral vasoconstriction if not prevented by alpha-adrenoblocking drugs. The SON stimulation entailed activation of both the synthesis and the transport of neurosecretory substances and increased the neurohormone release into the blood flow. Delayed ("hormonal") vasoconstrictory responses occurred in these experiments. Stimulation of the preoptic area evoked moderate cerebral vasodilatation, later decreased or blocked by atropine. Neurohormone (vasopressin) seems to participate in the vasoconstriction evoked by the SON stimulation.
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