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Title: A sensitive and dependable assay for distinguishing hamster and human X-linked steroid sulfatase activity in somatic cell hybrids. Author: Willard HF, Holmes MT. Journal: Hum Genet; 1984; 66(2-3):272-5. PubMed ID: 6585346. Abstract: A radioisotopic assay is described to distinguish between Chinese hamster and human steroid sulfatase activity in extracts prepared from hamster X human somatic cell hybrids. This assay is based on different pH optima and provides a sensitive and unambiguous biochemical marker for the short arm of the human X chromosome and as well as for otherwise genetically inactivated X chromosomes in rodent X human hybrids.[Abstract] [Full Text] [Related] [New Search]