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  • Title: Acute myelogenous leukemia following radiation therapy and chemotherapy for osteogenic sarcoma.
    Author: Jacobs AD, Gale RP.
    Journal: Cancer Treat Rep; 1984 Jun; 68(6):909-11. PubMed ID: 6587934.
    Abstract:
    Patients receiving ionizing radiation therapy or cytotoxic chemotherapy are at increased risk of developing acute myelogenous leukemia. Ten cases of therapy-linked myelogenous leukemia have been reported in patients with sarcoma, and we report here the first case in a patient who received combined-modality therapy for treatment of an osteogenic sarcoma. As treatment for this disease becomes more intensive and survival improves, the incidence of leukemia following therapy for osteogenic sarcoma may increase.
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