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  • Title: Histologic effects of Amipaque (metrizamide) and various contrast media on mouse peritoneum.
    Author: Berner A, Johansen JG.
    Journal: Invest Radiol; 1978; 13(2):161-2. PubMed ID: 659088.
    Abstract:
    The histologic effects of Amipaque and various commonly used contrast media on mouse peritoneum were studied by intraperitoneal injections of Amipaque 370 mg I/ml and 170 mg I/ml, Conray 300 mg I/ml, Conray Meglumine 282 mg I/ml, Urografin 60% and 76%, Gastrografin and barium sulfate. Amipaque and the other water-soluble media cause no deleterious effects, whereas barium sulfate evokes granulomatous inflammatory reaction. Amipaque is suitable for gastrointestinal studies when leakage into the peritoneal cavity is expected.
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