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  • Title: Double blind comparison between iohexol and metrizoate in phlebography of the lower limb.
    Author: Albrechtsson U, Fagher B, Lagerstedt C, Lárusdóttir H, Olsson CG, Westling H, Oqvist B.
    Journal: Acta Radiol Suppl; 1983; 366():58-64. PubMed ID: 6591741.
    Abstract:
    A new, non-ionic low osmolar contrast medium, iohexol 240 mg I/ml, has been tested in a randomized double blind parallel investigation versus meglumine-Ca metrizoate 200 mg I/ml. The study was performed to evaluate the suitability of the contrast medium in phlebography. No post-phlebographic complications were seen in the 24 patients examined with iohexol 240 mg I/ml or in 8 patients examined with iohexol 300 mg I/ml. In the 19 patients examined with metrizoate 200 mg I/ml, 7 had a post-phlebographic thrombotic complication (37%). The radiographic image quality was not significantly different between the two contrast media, neither were the immediate side effects during contrast injections. It has thus been shown that iohexol is a suitable contrast medium in phlebography of the lower limb and that it is preferable to conventional contrast media.
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