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  • Title: Influence of the peptide chain length of new elongated tuftsin analogs on phagocytosis process.
    Author: Konopińska D, Kazanowska B, Bogusławska-Jaworska J.
    Journal: Int J Pept Protein Res; 1984 Sep; 24(3):267-73. PubMed ID: 6594319.
    Abstract:
    In this paper the synthesis of the following elongated tuftsin analogs: Arg-Thr-Lys-Pro-Arg (1), Pro-Arg-Thr-Lys-Pro-Arg(II), Lys-Pro-Arg-Thr-Lys-Pro-Arg(III) and Thr-Lys-Pro-Arg-Thr-Lys-Pro-Arg(IV) by classical and solid-phase methods are described. The obtained peptides were tested for their biological activity: restoration of the phagocytosis of defected granulocytes from blood of children with acute lymphoblastic leukemia (ALL).
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