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  • Title: Bone marrow fibre content in acute myeloid leukaemia before and after treatment.
    Author: Islam A, Catovsky D, Goldman JM, Galton DA.
    Journal: J Clin Pathol; 1984 Nov; 37(11):1259-63. PubMed ID: 6594351.
    Abstract:
    Bone marrow fibre content was studied in 34 patients with acute myeloid leukaemia at presentation and subsequently after chemotherapy and at complete remission. The findings indicate that: some degree of marrow fibrosis is present in about one third of the patients with acute myeloid leukaemia at presentation; effective antileukaemia treatment may result in reversal of marrow fibrosis; and increase in marrow fibre content at diagnosis does not affect haemopoietic regeneration after treatment and achievement of complete remission.
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