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  • Title: Cytologic diagnosis of intravenous talc granulomatosis by fine needle aspiration biopsy. A case report.
    Author: Tao LC, Morgan RC, Donat EE.
    Journal: Acta Cytol; 1984; 28(6):737-9. PubMed ID: 6594887.
    Abstract:
    A fine needle aspiration specimen from the right lung of a 44-year-old former drug addict was submitted for cytologic evaluation. The specimen consisted of numerous mononucleate and multinucleate macrophages containing aggregates of silicate crystals, as seen by light microscopic examination using a polarizing filter. The background of the slides included fibroblasts, lymphocytes and other inflammatory cells. The finding within foreign-body giant cells of large groups of strongly birefringent, platelike crystals varying widely in size led to the conclusive cytologic diagnosis of intravenous talc granulomatosis.
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