These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Rat liver sulfotransferases: effects of gonadal hormones and other factors on enzyme activities.
    Author: Watanabe HK, Matsui M.
    Journal: J Pharmacobiodyn; 1984 Sep; 7(9):641-7. PubMed ID: 6597310.
    Abstract:
    Estradiol benzoate (EB), testosterone propionate (TP), progesterone (PG), corticosterone (CS), 3-methylcholanthrene (MC) and phenobarbital (PB) were administered to Wistar rats and their effects on hepatic sulfotransferase (ST) activities toward androsterone (AD) and 4-nitrophenol (NP) were determined. ST activity toward AD was increased by pretreatment with EB and PG in male rats. ST activity toward NP was increased by administration of TP and PG in females, whereas the enzyme activity was suppressed by pretreatment with EB in males. Administration of CS, MC and PB did not significantly affect ST activities toward AD and NP. These results indicate that sex difference in rat liver ST activities appears to be primarily regulated by androgenic, estrogenic and progestational hormones.
    [Abstract] [Full Text] [Related] [New Search]